Why aren’t we curing the world’s most curable diseases?

first_img Support conservation and fish with NEW Florida specialty license plate Ivermetcin is the same drug that is in Heartguard, which is sold to prevent heartworms in dogs. I had my big dog, C-Boy, on Heartguard until I had to have him put down, earlier this year due to a large tumor on his back leg, his mobility problems of getting up and now, and his advanced age. I was surprised to learn from this article that ivermetcin prevents river blindness, although I knew from the packs that it prevented hookworms, heartworms, roundworms, pin worms, and whipworms. If this is the drug that was a penny a pill, the drug companies sure charge a lot for Heartguard, as it was close to a hundred dollars when I bought it for C-Boy! The drug companies in this country are greedy! I don’t know why the president doesn’t do something about it! Once upon a time, the world suffered.In 1987, 20 million people across the world were plagued by a debilitating, painful and potentially blinding disease called river blindness. This parasitic infection caused pain, discomfort, severe itching, skin irritation and, ultimately, irreversible blindness, leaving men, women and children across Africa unable to work, care for their families and lead normal lives.But the recent discovery of a drug called ivermectin was about to change it all. Not only was ivermectin cheap and easily synthesized, but it was also a powerful cure: With only one dose a year, it was possible to completely rid patients of disease and even halt the progression toward blindness. In short, ivermectin was a miracle drug – one whose discovery would lead to Satoshi Omura and William Campbell winning the Nobel Prize in medicine in 2015.There was no time to be wasted. Recognizing that the populations most at risk of disease were those least able to afford treatment, Merck & Co. pledged to join the fight to end river blindness. Thirty years ago this October, the pharmaceutical company vowed that it would immediately begin distributing the drug free of charge, to any country that requested it, “for as long as needed.” It was the final piece of the puzzle: an effective drug for a tragic and completely preventable disease. And we all lived happily ever after.Only… we didn’t.Merck’s generous offer should have been the final chapter of a brief story with an upbeat ending – the eradication of a tragic and preventable disease that had plagued humankind for centuries. But such was not the case: 30 years later, in 2017, river blindness rages on across the world, afflicting as many as 37 million people, 270,000 of whom have been left permanently blind.Neglected tropical diseases like river blindness stand in stark contrast to those like tuberculosis, which is estimated to affect a third of the world’s population due to the increasing prevalence of highly antibiotic resistant strains.In short, tuberculosis has stuck around because medicine has run out of drugs with which to treat it – which is why, as a molecular biologist, I am researching new ways we can finally defeat this stubborn disease.But this only increases the urgency for river blindness and other widespread diseases for which, unlike tuberculosis, science does have effective cures – and inexpensive ones at that. Even with all the necessary tools, the world has failed to cure the curable.Turning a blind eyeOne-and-a-half billion people across the world suffer from neglected tropical diseases, a group of infectious diseases that prevail in tropical and subtropical countries lacking good health care infrastructure and medical resources. These diseases typically do not kill immediately but instead blind and disable, leading to terrible suffering, creating losses of capital, worker productivity and economic growth.Thirteen diseases are universally recognized as neglected tropical diseases. At least eight of these diseases, including river blindness, already have inexpensive, safe and effective treatments or interventions.For less than 50 cents per person, the United States could cure a fifth of the world’s population of these severely debilitating and unnecessary diseases. In spite of this, the United States allocates nearly as little to treating and preventing neglected tropical diseases around the world as it does to drugs for erectile dysfunction.The forgotten feversConsider dracunculiasis, or Guinea worm infection, which occurs when people consume water contaminated with fleas carrying parasitic worms. The worms mature and mate inside the human body, where they can grow to be two to three feet long.A girl in Juba, South Sudan, has a Guinea worm extracted from her leg. Reuters/Skye WheelerAdult females eventually emerge from painful blisters at the extremities to lay eggs in stagnant water, where offspring will infect water fleas and begin the cycle anew.No drug exists that can cure Guinea worm, but because of a cohort of mostly privately funded public health efforts, the number of Guinea worm infections worldwide has dropped from 3.5 million in the 1980s to only 25 in 2016.Funding from the U.S. and other countries could help in the final push to eradication, and some argue that funding from the individual countries themselves could help.Another example, albeit more grim, is the group of soil-transmitted helminths, or worms. Roundworm, hookworm and whipworm collectively affect over a billion people across the world, all in the poorest areas of the poorest countries. All these worms infect the human intestines and can cause severe iron deficiency, leading to increased mortality in pregnant women, infants and children. Furthermore, hookworm infections in children retard growth and mental development, leading to absences from school and dramatically reduced labor productivity.However, soil-transmitted helminths can be expelled from the body with a single pill, each of which costs only one penny. What’s more, preventing infection in the first place is completely achievable through increased awareness and sanitation.The purse strings of nationalismWithout drastic increases in funding and public awareness, the plight of people affected by the neglected tropical diseases is unlikely to budge anytime soon.The U.S. spends over US$8,000 per person per year on health expenditures, compared to countries in Africa that spend around $10. While this opens the door to a critique on efficiency, it’s far more indicative of the disparities in health resources.Less than 20 percent of the world’s population lives in some of the most developed and economically high-functioning countries, including the United States – and nearly 90 percent of the world’s total financial resources are devoted to the citizens of these nations. And yet, low-income countries bear the majority of the world’s infectious disease burden. In short, the rest of the world does not suffer the same diseases the United States does, and Americans are doing little to nothing about it.At first glance, this is not so surprising. As a whole, the world suffers – but how many neglected tropical diseases currently penetrate American borders?Some experts predict that eliminating or controlling the neglected tropical diseases in sub-Saharan Africa alone, which shoulders over 40 percent of the global burden of neglected tropical diseases, could save the world $52 billion and over 100 million years of life otherwise lost to disease.Conversely, some global health experts estimate that for every dollar spent on neglected tropical disease control, we get back over $50 in increased economic productivity. By increasing awareness and funding of neglected tropical disease eradication, the United States will be making one of the best global investments possible. The rest of the world has waited long enough.Katherine Wu is a PhD candidate studying tuberculosis at Harvard University. She graduated from Stanford University with masters and bachelors degrees in biology. Currently, she is Co-Director of Science in the News, a graduate student organization committed to training student scientists to better communicate their science to the public. By Katherine Wu, first published in conversation.com Please enter your name here October 30, 2017 at 9:38 am You have entered an incorrect email address! Please enter your email address here Save my name, email, and website in this browser for the next time I comment. TAGSconversation.com Previous articleIn case you missed it: The Apopka news week in reviewNext articleFlorida Hospital hosts second collection drive for Puerto Rico Denise Connell RELATED ARTICLESMORE FROM AUTHOR Reply Free webinar for job seekers on best interview answers, hosted by Goodwill June 11 Share on Facebook Tweet on Twitter LEAVE A REPLY Cancel reply Please enter your comment! Mama Mia 1 COMMENT The Anatomy of Fear last_img read more

Amwaj Villa / MORIQ

first_img Lead Architects: Architects: MORIQ Area Area of this architecture project Houses Amwaj Villa / MORIQ CopyAbout this officeMORIQOfficeFollowProductConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesOn FacebookBahrainPublished on January 10, 2021Cite: “Amwaj Villa / MORIQ” 09 Jan 2021. ArchDaily. Accessed 10 Jun 2021. ISSN 0719-8884Browse the CatalogSinkshansgroheBathroom Mixers – LogisVinyl Walls3MExterior Vinyl Finish – DI-NOC™ StonePartitionsSkyfoldWhere to Increase Flexibility in SchoolsTiles / Mosaic / GresiteCupa PizarrasVentilated Facade – CUPACLAD UprightGlassLAMILUXGlass Roof PR60ConcreteKrytonCrystalline Waterproofing – KIMSkylightsVELUX CommercialAtrium Longlight Skylights in ExperimentariumMetal PanelsLorin IndustriesAnodized Aluminum – Copper FinishesStonesFranken-SchotterWall Covering & CladdingWindowsRabel Aluminium SystemsMinimal Casement Windows – Rabel 8400 Slim Super Thermal PlusSwingsStudio StirlingHanging Chair – BasketWallcovering / CladdingArrigoni WoodsWood Cladding – AcousticMore products »Save世界上最受欢迎的建筑网站现已推出你的母语版本!想浏览ArchDaily中国吗?是否翻译成中文现有为你所在地区特制的网站?想浏览ArchDaily中国吗?Take me there »✖You’ve started following your first account!Did you know?You’ll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my stream CopyHouses•Bahrain ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/954404/amwaj-villa-moriq Clipboard Year:  Amwaj Villa / MORIQSave this projectSaveAmwaj Villa / MORIQ ArchDaily Manufacturers: Jotun, Roche Bobois, Bespoke, FLOS, Greece Manufacturers Brands with products used in this architecture project center_img Save this picture!Courtesy of MORIQ+ 16Curated by Hana Abdel Share ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/954404/amwaj-villa-moriq Clipboard Area:  778 m² Year Completion year of this architecture project Bahrain “COPY” 2015 “COPY” Projects Riyaz Quraishi, Simeen Quraishi Interior Designers:MoriqLandscape Architects :MoriqProject Construction:Ghumais Constructions Company W.L.L, BahrainMEP & HVAC:Ghumais Constructions Company W.L.L, BahrainProject Management :Ghumais Constructions Company W.L.L, BahrainCountry:BahrainMore SpecsLess SpecsSave this picture!Courtesy of MORIQRecommended ProductsWindowsOTTOSTUMM | MOGSWindow Systems – BronzoFinestra B40WindowsJansenWindows – Janisol PrimoEnclosures / Double Skin FacadesIsland Exterior FabricatorsCurtain Wall Facade SystemsMetallicsTECU®Copper Surface – Classic CoatedText description provided by the architects. The house was meant for a single family, situated in a posh locality in Amwaj, Bahrain. The plot was 690 sqm and the total built came up to 778 sqm/8371sft. The owners wanted a modern, contemporary styled home with strong emphasis on interior architecture and strong interior/exterior connections.Save this picture!Courtesy of MORIQSave this picture!Ground Floor PlanSave this picture!Courtesy of MORIQThe home was planned on 3 levels with just the living levels and kitchen plus dining on the lower floor. A well equipped gym with steam and sauna were planned on the rear side. Two bedrooms with a non dedicated home theatre comprises the mid level. Master suite with multi dress rooms and multi toilets is planned on the last level. All three levels are connected by means of a staircase and a lift. Difference of levels and double heights perk up the interiors. Large floor to ceiling glasses connect the outside with the inside.Save this picture!Courtesy of MORIQSpecks of colors were used in furniture and artifacts only keeping the basic canvas neutral  (in greys and whites). Grey white travertine were used as floors. Walls were in shades of greys and ceiling were pristine white. Distressed wallpapers were used on strategic walls. A custom designed chimney is the center of attraction in the dining area. A large scaled log of wood was used as the grab bar for the staircase. Skylights bring in a lot of natural light.Save this picture!First Floor PlanSave this picture!Courtesy of MORIQOld reclaimed doors as used as interior elements. Every room has visual and physical access to the outside. Furniture is from Italian brands. Rugs and lamps are all hand picked. As mentioned earlier the emphasis was more on scale, proportions and integration rather than on decoration. The final look is simple and uncluttered both in architecture and interior.Save this picture!Courtesy of MORIQProject gallerySee allShow lessLes Domaines Ott Château de Selle / Carl Fredrik Svenstedt Architect | CFSASelected ProjectsAmazon Blink Studio / Ultraconfidentiel DesignSelected Projects Sharelast_img read more

Council seeks public opinion on Abbeyfeale traffic proposals

first_imgNew parklet changes Catherine Street dining experience O’Donnell Welcomes Major Enhancement Works for Castletroy Neighbourhood Park Council seek public opinion on Abbeyfeale traffic plan.Limerick City and County Council has drawn up plans for a new traffic management system in Abbeyfeale and is now looking for the views of the public on the proposals.A public information day will be held in Leens Hotel, The Square, Abbeyfeale on Thursday, January 18 from 12 noon until 8pm. Council officials and staff from the consultants will be on hand to go through the plans take any questions arising from the process.Among the proposals are:Sign up for the weekly Limerick Post newsletter Sign Up ​Modified traffic lane widths along the N21 within Abbeyfeale town centre with revised parking layout.New traffic signals at the Main Street/ Church Street and Main Street/ Colbert Terrace junctions with controlled pedestrian crossings.Realignment of the junction at Main Street/ St. Ita’s Road.Upgrade of mini roundabout junction at Colbert Terrace/ Tesco.Development of a pedestrian link between Main Street and Grove Crescent public car park.New coach parking and set downs areasLimerick City and County Council would like to know your opinions.All submissions or observations must be made in writing to The Planning and Environmental Services Department, Limerick City and County Council, Dooradoyle, Limerick V94 WV78 on or before 4pm on Thursday, February 8.More information here TAGSAbbeyfealeChurch StreetColbert TerraceGrove CrescentLimerick City and County CouncilMain StreetPublic consultationSt It’s Roadtraffic plan RELATED ARTICLESMORE FROM AUTHOR Twitter Linkedin Ireland’s First Ever Virtual Bat Walk to take place in Limerick Email Call to extend Patrickswell public sewer line center_img Limerick’s O’Connell Street Revitalisation Works to go ahead Advertisement WhatsApp €1.5 million boost for five County Limerick towns from Rural Regeneration and Development Fund Previous articleLimerick advocates needed to help young people reach their potentialNext articleThe return of Kevin Barry for Limerick Literary Festival Editor Facebook NewsCouncil seeks public opinion on Abbeyfeale traffic proposalsBy Editor – January 9, 2018 2269 Printlast_img read more

LAST OF THE BUFFALO HUNTERS

first_imgLAST OF THE BUFFALO HUNTERSGavel Gamut By Jim Redwinewww.jamesmredwine.comBefore he served our country in Viet Nam my friend Jimmie Reed worked on his dad’s ranch in Foraker, Oklahoma. Jimmie and Bill Moon and I played football for the Pawhuska, Oklahoma Huskies and graduated together in 1961. The summer between our junior and senior years Jimmie’s father, Phil Reed, needed some fence built and Jimmie volunteered Bill and me to help. Mr. Reed paid us $7.00 per day plus a hamburger at lunchtime at the old Foraker store.One typical Osage County July day Mr. Reed and Jimmie came into Pawhuska at 6:00 a.m. and picked up Bill and me to work. If you have never had the experience of building a barbed wire fence across a pasture of unyielding Osage County sandstone where shade is illegal, may I advise you to maintain your current status? We were equipped with bales of barbed wire, wire cutters, wire stretchers and, surprisingly to me as a town boy, sledgehammers and long iron pikes. Oh, we had manual post hole diggers but they shrank in fear when encountering two inches of topsoil over two feet of rock.About the only way to drive a metal fence post deep enough to hold stretched out wire was to first stand on the tailgate of a pickup and make a hole by driving down an iron pike with a sledgehammer. Then we had to drive a post into the hole.That particular bucolic summer day on the prairie as I dodged the zooming grasshoppers and wondered how I was going to pay Jimmie back later by beating him at snooker at the local pool hall if we made it to dark, a cowboy from the nearby Boots Adams ranch drove up and spoke to Mr. Reed. Mr. Reed who was usually calm and laconic got agitated. I overheard him tell the cowboy something had to be done right away. Mr. Reed used a couple of emphatic words I had never heard him utter before.Gentle Reader, you are probably wondering why Mr. Reed and Boots did not simply discuss the matter via their cell phones. Well, in 1960 a pickup was the cell phone. Anyway, the cowboy took Mr. Reed’s comments back to Boots. Here’s what it was all about.Boots Adams, who was once the president of Phillips Petroleum Company headquartered in Bartlesville, Oklahoma, used to regale eastern dude money men with the great golden west by introducing them to cowboys, horses, cattle and the small herd of buffalo he kept at his ranch. We called them buffalo before the Nature Conservancy opened shop and made us say bison. It turns out bison and cattle are kind of like Democrats and Republicans. They generally do not play well together. So, Mr. Reed told Boots’ cowhand something had to be done when the cowhand said seven of Boots’ buffalo had broken out and were causing havoc among Mr. Reed’s cattle.Well, Boots’ cowboy hurried back to Boots with Mr. Reed’s concerns then returned. I heard the cowhand say, “Boots said to just shoot ‘em”. Actually, Boots used somewhat more colorful vernacular. As for the cowhand he produced several rifles and ammunition and told Mr. Reed that Boots was sending a flatbed truck with a wench to meet up with us where the buffalo were roaming.Mr. Reed, Jimmie, Bill, the cowhand and I jumped into the two pickups and flew off to hunt buffalo! It was not long before we found the burly beasts ambling around Mr. Reed’s pasture as though they belonged there. And just as the politically incorrect buffalo hunters who used to kill herds of buffalo from a train’s flatcar, we removed the seven marauding behemoths.Please do not castigate us, the last of the buffalo hunters, for protecting the cattle. It was a job that had to be done. And it sure beat building fence. I wish Jimmie and Bill, and Mr. Reed too, were still here to fill any gaps in my recollection. On the other hand, I know wherever they are they are cooler than in The Osage in July and are perhaps still chasing after some mystical buffalo instead of pounding down fence posts.For more Gavel Gamut articles go to www.jamesmredwine.comOr “Like” us on Facebook at JPegRanchBooks&KnittingFacebookTwitterCopy LinkEmailSharelast_img read more

However, Austria rejected Croatia’s request: the whole of Croatia remains on the red list

first_imgSlovenia, the Netherlands, Germany The warning against travel to Croatia is in force from Monday at midnight. Returnees from holidays from Croatia must show a current negative test for coronavirus or undergo testing within 48 hours.  Side dish: List of Croatian laboratories for testing on COVID-19 The warning has been active since Monday, and this measure has logically forced many Austrian tourists to interrupt or postpone their vacation in Croatia and return to Austria. As we know that Austria is one of our main emitting markets, this is certainly a big blow for our tourism, especially for the extension of the tourist season, ie the post-season. The decision of Slovenia, ie the Netherlands, is expected on Thursday, and the positive news is that we are still on the green list in Germany. Laboratories where the COVID-19 test in Croatia can be performed can be found in the attachment. center_img Source: RTL.de However, Austria rejected Croatia’s request that the epidemiological situation in Croatia be viewed through the regions, and not for the entire territory of Croatia, reports the Austrian news agency APA. The situation is as it is, we have to adapt again and turn to new markets, and the focus should certainly be on domestic guests. As we know, Austria has put Croatia on the red list, and to enter Austria you need a NEGATIVE PCR test or be tested in Austria within 48 hours at your own expense. last_img read more

Providence Adds Senior Independent Director

first_imgProvidence Resources, the Irish based oil & gas exploration company, has appointed Dr Angus McCoss as senior independent director with immediate effect.  Dr McCoss joined the Providence board as a non-executive director in June 2017.Pat Plunkett, chairman of Providence Resources said: “We are delighted that Angus is taking on the role of senior independent director and are confident that he will bring the same wealth of experience to this position as he has provided to the board since joining in 2017.”Dr Angus McCoss is the exploration director and a main board director of Tullow Oil and is a non-executive director of Ikon Science.cDr McCoss joined Tullow in 2006 following 21 years of wide-ranging exploration experience, working primarily with Shell in Africa, Europe, China, South America and the Middle East.He held a number of senior positions at Shell, including regional vice president of Exploration for the Americas and general manager of Exploration in Nigeria.Dr McCoss holds a PhD in Structural Geology and is a member of the advisory board of the industry-backed Energy and Geoscience Institute at the University of Utah.last_img read more