TagsTransfersAbout the authorFreddie TaylorShare the loveHave your say Mkhitaryan faces exit if Arsenal complete move for Denis Suarezby Freddie Taylor10 months agoSend to a friendShare the loveArsenal’s move for Barcelona midfielder Denis Suarez could force Henrikh Mkhitaryan to leave the Emirates.The Armenian international, who is currently sidelined with a foot injury, has failed to impress since joining from Manchester United last January. And The Sun claims the Gunners are ready to sell Mkhitaryan in order to make room for Suarez.The 25-year-old is believed to be on the verge of joining the north London club, having previously worked with manager Unai Emery at Sevilla.Suarez, who started his career at Manchester City, has played 17 minutes of league football this season.
Amaravati (AP), Mar 7 (PTI) Andhra Pradesh Chief Minister N Chandrababu Naidu on Thursday alleged the Modi government was trying to silence the media through “unconstitutional means”, condemning the Centre’s threat of invoking action under the Official Secrets Act (OSA) against The Hindu newspaper in the Rafale case.The government Wednesday told the Supreme Court that documents related to the deal were stolen from the Defence Ministry and threatened the newspaper with action for publishing articles based on them. Also Read – How a psychopath killer hid behind the mask of a devout laity!”Instead of coming clean on alleged irregularities of Rafale deal brought out by The Hindu and Mr N Ram, the Modi govt is trying to silence the press through unconstitutional means by creating a climate of fear. It signals an imminent possibility of the breakdown of democracy,” the chief minister tweeted. “After misguiding SC, misleading the nation, destroying all vital institutions of the country, Modi govt’s threat to file cases under Official Secrets Act against The Hindu and Mr N Ram is a serious threat to freedom of speech & expression guaranteed by the Constitution of India,” he claimed. Attorney General K K Venugopal had said before a three-judge bench headed by Chief Justice Ranjan Gogoi that those who put documents on the Rafale deal in the public domain are guilty under the act and contempt of court. Unruffled by the Centre’s stand, Hindu publishing group Chairman N Ram had said nobody would get any information from the newspaper on the confidential sources who provided the documents.
Raigad (Maharashtra): Authorities here on Friday carried out a controlled blast to raze the luxurious beach bungalow of absconding diamantaire Nirav Modi, one of the prime accused in the Punjab National Bank scam, official sources said. Over 100 dynamite sticks were strategically placed within and outside the bungalow near Kihim beach, and the blast took place at 11.15 a.m. amidst tight security, said an eyewitness from the site. Few days ago, detonators were fixed at various points on the bungalow – located around 110 km from Mumbai – to carry out the ‘implosion’ and bring it down in a single-shot. Also Read – IAF Day: Tributes paid to soldiers killed in line of duty in Jammu With the complete structure razed to the ground, labourers will now start the work of removing the debris from the venue over the next couple of weeks. On January 25, the Collectorate had initiated the demolition process using traditional methods of bulldozers, excavators and other such manually-operated equipment, but it proved to be a slow and tedious process. Attached by the Enforcement Directorate (ED) in December 2018, the bungalow was stripped off all its valuables, art works, paintings and other expensive items. All glass structures were removed to enable the controlled blasting. Also Read – Shashi Tharoor writes to PM Modi: Don’t let your ‘mann ki baat’ become ‘maun ki baat’ Modi, along with his uncle Mehul Choksi and others, are the prime accused and fugitives in the Rs 14,000-crore Punjab National Bank (PNB) fraud admitted in February 2018. Though the Alibag bungalow was not directly linked with the PNB scam, it was attached by the ED along with his known assets in Maharashtra, Gujarat and other places in an effort to recover a part of the dues from Modi. Built in 2009-2010, on a 70,000 square feet plot, the 33,000 square feet bungalow with several bedrooms is accessible through a long driveway, protected by high metal fencing and a huge security gate, and was noted for lavish parties hosted here regularly. The demolition process followed orders of the Bombay High Court in a Public Interest Litigation filed by NGO Shamburaje Yuva Kranti (SYK), seeking action against various illegal bungalows, hotels and resorts violating the high tide and low tide zones in tiny villages dotting the beaches of Raigad. SYK state chief Surendra Dhavale said that so far 10 bungalows have been demolished in the past few months, and now Modi’s bungalow was razed, with at least another four dozen on the Collector’s demolition list. “The claimed value of the (Modi) property is cited as Rs 13 crore, but given the current market rates, this bungalow is worth over Rs 100 crore,” Dhavale told IANS. Besides, Choksi – now a citizen of Antigua & Barbuda, many celebrities, industrialists, top businessmen, film and television personalities own big and small properties on this picturesque stretch of central coastal Konkan region, barely an hour’s boat ride from the mainland at Gateway of India.
New Delhi: “There should not be any form of child labour during the upcoming Lok Sabha Polls,” wrote the Delhi Commission for Protection of Child Rights (DCPCR) to District Magistrates inDelhi. The DCPCR letter accessed by Millennium Post reads that “Lok Sabha election is likely to be held in the month of April/May 2019.” “Your attention is invited to the letter written by the secretary of the Election Commission of India in the year 2017 regarding the prohibition of the use of children by political parties during election campaigns and engagement of child labour in the election-related activities.” Also Read – Gurdwara Bangla Sahib bans single use plastic”It should be ensured by all political parties and election officials that children are not involved in any election-related process and activities with the directions may be followed by all meticulously, “reads the DCPCR letter adding that non-compliance of the directions contained therein be brought to the notice of this commission. Roop Sudesh Vimal member DCPCR had written the letter. The child rights body also attached a letter reportedly written by the National Commission for Protection of Child Rights (NCPCR) in 2017 regarding the use of children by political parties during the election Also Read – After eight years, businessman arrested for kidnap & murdercampaign. “All the officials deputed in the election process should ensure that children are not involved in any form of carrying EVMs or other materials to the election booths, strong rooms, godowns,” claimed the letter. It further added that all political parties~National, as well as State level~be directed not to use children in the election campaign in any form whatsoever, for distribution of posters, pamphlets or to participate in slogan shouting, campaign rallies, election meetings.
Kolkata: West Bengal police assistant sub inspector Rudra Prasad Halder, who had successfully scaled the Mount Everest in 2016, will soon embark on Kanchenjunga expedition.Halder, who presently works with the wireless department of Bengal police, is a mountaineer with repute and has already successfully made 21 mountain summits, the most notable one was the Mount Everest when he reached its summit on May 21, 2016. Sharing his expedition plan with the Millennium Post, Halder said: ” I will leave for Kathmandu from Kolkata airport on Thursday and will staying there Saturday. The main expedition will start from Taplejung on April 8 and after walking for 11 days we will be reaching the base camp of Kanchenjunga. Then it will take another 40 to 45 days tentatively to climb up to the summit which has a height of 8586 metres.” Mountaineer Biplab Baidya and two other climbers will accompany Halder in the expedition. Kanchenjunga happens to be the third highest mountain peak in the world. ” I am grateful to the Bengal police for funding my expedition. My seniors have always encouraged and supported me. It was Director General (DG) Virendra (Sir) who flagged off my expedition on Tuesday,” Halder said. He recollected the fateful day of May 20, 2014 when mountaineer Chhanda Gayen went missing along with two sherpas in an avalanche while descending the western side of Mount Kanchenjunga in Nepal. Later, it was declared all three of them died in the avalanche. Halder had attempted to scale the Mount Everest in 2015 but had to stall his expedition due to the devastating earthquake in Nepal. Halder was trained at Uttarkashi’s Nehru Institute of Mountaineering. He is associated with a Sonarpur-based trekking club Arohi. It may be mentioned that there are four climbing routes to reach the summit of Kanchenjunga, three of which are in Nepal— from the southwest, northwest and northeast— and one from northeastern Sikkim in India. Till date, the northeastern route from Sikkim has been successfully used only three times. The Indian government has banned expeditions to Kanchenjunga, and therefore this route has been closed since 2000.
New Delhi: More than 45,000 complainants with their grievances visited city police stations till March this year. The law enforcement agency after listening to their complaints registered over 6,000 FIRs in different cases.Police sources said that 34,140 complainants met Public Facilitation Officers whereas the concern of 14,194 people was heard by the Station House Officers (SHOs) or Additional SHOs of more than 180 police stations and units in Delhi Police. Sources further told this newspaper that 39,800 complaints relating to different natures including sexual assault, robbery, kidnapping, hurt, theft, quarrel, cheating, forgery and others came. Also Read – After eight years, businessman arrested for kidnap & murderThe nature of 563 complaints was regarding sexual assault whereas 18,65 complaints were related to missing and kidnapping. The complaints pertaining to snatching, robbery and theft were 4,982. “As many as 4570 complaints came to police related to hurt, threats and quarrel whereas in cheating and forgery 2,164 complaints were heard,” said sources adding that other complaints were 23,920. In a recent meeting, the Police Commissioner reviewed the status regarding handling of complaints at police stations and prompt registration of cases. The police chief also discussed the disposal of pending investigation cases and period of pendency of these cases especially rape and POCSO. The top cop also reviewed the status of computers with internet connections of facilitation desks in police stations. Also Read – Two brothers held for snatchingsSources said that out of 189 police stations, 183 have PFO desk. In 85 police stations, PFOs have computer connectivity whereas in 56 stations, internet is being provided. Recently, the office of LG Anil Baijal wrote to Delhi Police for providing internet connection to Public Facilitation Desks. “It has also been desired to provide an internet connection in Public Facilitation Desks so that these Desks can facilitate the lodging of e-fir as well,” sources said quoting letter content. According to Delhi Police Annual Report of 2018, as many as 2,36,476 IPC cases were registered during the year as against 2,23,077 in 2017. The report further said that the criminal activities and space, are getting integrated, syndicated and globalised. Consequently, they pose a challenge not only to the law enforcement agencies but also to the civil society in general. Incidents in Delhi are the focus of attention not only for the National Media but also to world media and even ordinary crimes and disorders tend to be sensationalized causing an unsettling effect on the minds of the people and their perception of the functioning of the police.
New Delhi: Aviation regulator DGCA will continue to monitor airfare movements on a daily basis and also engage with airline for appropriate action, a senior official said Tuesday amid concerns over rising ticket prices. With crisis-hit Jet Airways drastically curtailing its operations, there has been an adverse impact on the number of flights being operated on various routes. As concerns persist on higher air ticket prices, the Directorate General of Civil Aviation (DGCA) Tuesday held a meeting with representatives of airlines, the official said. Also Read – India gets first tranche of Swiss bank a/c details Airlines were advised to continue to monitor at their level and provide information to the DGCA to keep fares low as far as possible, he noted. “Airlines representative also intimated DGCA that they have removed the few higher buckets from sale and offering tickets to passengers in lower fare buckets. “DGCA will continue to monitor fare movement on daily basis and engage with airline for appropriate action,” the official added. According to him, the regulator monitors domestic airfares on a daily basis, particularly on high density routes and routes where alternate mode of transport is not available or is difficult. Also Read – Tourists to be allowed in J&K from Thursday Based on the monitoring process, the DGCA engages with airlines when the spurt in airfares is observed in any sector for appropriate action, he added. Earlier in the day, Civil Aviation Minister Suresh Prabhu had called for a review of issues related to struggling Jet Airways, including rising fares and flight cancellations. “Directed Secretary @MoCA_GoI to review issues related to Jet Airways, especially increasing fares, flight cancellations etc,” Prabhu said in a tweet. Besides asking Civil Aviation Secretary Pradeep Singh Kharola to take necessary steps to protect passenger rights and safety, Prabhu also called for working with all stakeholders for their well being.
Kolkata: Union Defence secretary Sanjay Mitra on Saturday urged the management students of International Management Institute (IMI), Kolkata, to contribute towards making the life of the poor and deprived in the county better. “As alumni of this prestigious school, the array of possibilities for carving out a successful career is waiting for you. By all means make money, get rich, be successful but somewhere in some corner of your mind, do keep a thought of how your achievements can translate into contributing towards making the life of the poor and needy better,” Mitra said, addressing the 7th Convocation of IMI, Kolkata, on Saturday. Also Read – Bengal family worships Muslim girl as Goddess Durga in Kumari PujaMitra further reminded the students about their role in chartering the country to its progress path in the days to come. “Our country, with its immense reserve of human and physical resources, is lacking not in the quantity and quality of these resources but in the way we have utilised them. You, with your intellect and training, can bring on board the much-needed competence and balance to the field of public administration, thus becoming a part of the nation building process. I urge you to consider this as an option in your endeavours,” he said. 125 students of the premier management institute that includes 49 girls received their PGDM at the Convocation. Arindam Banik, director of IMI Kolkata, spoke about the institute’s growing number of international collaborations with business schools in France, China and Finland. “We have received 3,500 applications in PGDM from 29 states across India which clearly proves the growing popularity of the institute,” Banik maintained.
Roberto Cavalli is proud to announce the opening of the world’s first Cavalli Club in Dubai.Roberto Cavalli continues to surprise his public as he launches a new “entertainment & night-life” concept called Cavalli Club. The first Cavalli Club is scheduled to open in November 2008 in Dubai and is located within the Fairmont Hotel on Sheikh Zaved Road, one of the city’s most elegant streets. The club will consist of two floors, spanning a total of 2500 square meters and has its own private entrance separate from the hotel.Roberto Cavalli partnered with the Pragma Group for this important undertaking. Founded in 2003, the Pragma Group is the leading investment, outsourcing and business incubator holding, based in the UAE. With an expansive portfolio of international companies, the Pragma Group has opened in many key markets, such as technology and telecommunications, marketing, hospitality, entertainment and venture capital.Roberto Cavalli declared: “Dubai is a city of the future and the Cavalli Club is a futuristic space created with a global perspective. Dubai reflects the third millennium that has just started, and that will continue by proposing new expressions that can change the habits of the world. Living against monotony, with the enjoyment of music, of good food, of pleasant company is the Cavalli Club philosophy, and Dubai is opening the windows of tomorrow onto this project.”Cavalli Club is designed so that the architecture, furnishings, and the interiors selected effuse luxury and exclusivity; each area in the space creates an atmosphere rich with exciting shapes, structures, and precious materials. Black quartz floors shine with crystal dust reflecting light and shape throughout the space while six-meter high walls dripping with Swarovski crystals illuminate the room.On the ground floor, the entrance hall leads to a large room showcasing jewelry, watches and the most exclusive accessories from the Cavalli Maison. This, together with a selection of refined food products chosen specially by Roberto Cavalli to express the best of “Made in Italy”, offers to the public a complete Roberto Cavalli lifestyle experience and a new way of shopping at a non-conventional time of day.On the top floor, guests are offered multiple culinary and sensorial experiences. A refined and elegant Italian restaurant is at center of the hall, offering unforgettable, authentic Italian “cuisine”. On either side of the Italian restaurant, are two large atolls in gold-colored glass and fur, suspended from the floor, which host a sushi bar and a wine bar.For those opting for Japanese, the sushi bar offers a relaxed atmosphere for dining where guests can recline on sofas in front of low tables. The wine bar offers high quality selection of drinks from the prestigious Cavalli Selection red wine to the uniquely-designed bottle of the Roberto Cavalli Vodka. Guests can also sample Cavalli-signed chocolates, have a coffee or sip cognac within the smoking area.Parallel to the restaurant is a lounge bar that offers a chic and sensual environment for those wanting to try some exotic light food such as sushi and caviar. In this area, music plays until the early hours of the morning and guests can dance to hypnotic rhythms mixed by the best international DJs. A suspended platform will host the DJ and the dancers, as well as other entertainments and shows.With meticulous attention to detail, every element is thought out and executed perfectly to create a unique and ideal place for relaxation and enjoyment. The Cavalli Club’s innovative schedule offers light lunch, lunch, aperitif, pre-dinner, dinner and disco set; truly catering to the guests and allowing the experience of a luxury Club from day to night, in true Cavalli style.The Cavalli Club Dubai will open in November 2008, with Florence to follow by the end of the year. Openings in other major cities worldwide are expected within the next few years.
Ziggo’s main shareholders, private equity firms Cinven and Warren Pincus, are due to sell a 20% stake in the Dutch cable operator business. The sale will see the pair sell 40 million shares, at an estimated price of some €1 billion, and will leave them with a combined 17.1% of the business.The move comes a day after Ziggo said that it had received loan commitments from a number of banks to raise €800m, to partially refinance its existing debt. It said at the time it was also looking at additional refinancing options including a capital markets transaction.Ziggo said the price per share and the final number of shares sold in the new offering will be decided after determining investor demand.
The Mobile Video Alliance (MVA), an organisation set up set up last year to tackle issues like video quality over mobile networks, has officially launched today with support from UK industry body the Digital TV Group (DTG).UK culture minister Ed Vaizey launched the MVA at the DTG summit in London at what the alliance’s backers said was “a critical time for both the broadcast and mobile industries.”The MVA was established last year by interconnection and data centre firm Equinix and mobile operator EE to tackle technical issues such as the evolution of caching and adaptive bitrates and value chain fragmentation.It also comes at a time of rising mobile data traffic and increasing demand for video content from consumers, thanks to next generation WiFi and 4G mobile data networks.With the formal launch of the MVA, Equinix said it will make its recently launched solution validation centre available to MVA members to test new standards and configurations.“This makes us a vital interconnection platform for mobile video delivery and we are committed to encouraging and enabling the mobile video ecosystem,” said Michael Winterson, vice president of sales and marketing, Equinix EMEA.
Soumya SriramanBritBox, the forthcoming US subscription VOD service from BBC Worldwide and ITV, has appointed Soumya Sriraman as president, North America.Sriraman, who was most recently executive vice-president of franchise and digital enterprises at BBC Worldwide North America, takes up her new role effective immediately.She will be responsible for the overall strategy and operation of BritBox, which is due to launch later this quarter, and will focus on bringing “the best British content to the service” through acquisitions, licensing, co-productions, and partnerships.“Soumya has an outstanding historical knowledge and familiarity with British content. This, coupled with her creativity and excellent business acumen makes her the ideal executive to fill this role,” said Ann Sarnoff, president, BBC Worldwide North America.”“I am confident that Soumya is going to make this service a success, as she has done in all her endeavors for the last five years at BBC Worldwide North America.”Sriraman brings more than 20 years of entertainment experience to the role. Prior to working at the BBC’s commercial arm she was CEO of Anglo-American film distribution company, Palisades Tartan. She has also held senior executive positions at Universal, Warner, and Vivendi.Simon Pitts, ITV managing director of online, pay TV and interactive said: “BritBox is a very exciting development for fans of British TV and a natural next step in ITV’s growth as a global production and distribution business. I’m delighted that we have someone with Soumya’s knowledge, experience, and passion for British content spearheading the service as we prepare for the US launch.”BBC Worldwide and ITV announced their BritBox venture in December. The commercial arm of the UK public caster, and UK commercial broadcaster ITV will share a majority stake in the new venture, which they plan to roll out to other international markets after the US.BBC Worldwide North America is the main commercial arm of the BBC operating in the US and Canada. It also owns a 50.1% share in cable channel BBC America through a joint venture with AMC Networks.
Viacom has acquired VidCon, a conference focused on YouTube content creators and their fans, in a move designed to boost its live event and digital businesses.The channel group, which owns youth brands MTV and Nickelodeon, said that VidCon will remain a stand-alone entity, retain its senior leadership team, but will be able to “expand its global reach”.Viacom said the deal will accelerate its participation and investment in next-generation platforms, following its establishment of Viacom Digital Studios in November and its acquisition of influence marketing firm WHOSAY last month.The agreement also plays into Viacom CEO Bob Bakish’s long-term strategy to “considerably increase” the number, reach and impact of live events in the company’s portfolio.“VidCon has become the foremost gathering place for the passionate online video community, and the access to talent, experts and education that VidCon provides for attendees is unparalleled,” said Jason Jordan, Viacom executive vice president of multiplatform strategy and operations.VidCon CEO Jim Louderback and co-founder Hank Green will continue to lead the event from its offices in Missoula, Montana. Viacom said it will “simply provide more resources and a bigger microphone” to allow VidCon to continue nurturing the online video community.“We’re huge fans of the VidCon team, and we share the same enthusiasm for the power of connecting talented creators with their incredible fan communities,” said Kelly Day, president of Viacom Digital Studios.“This team has built an unprecedented live experience that brings together the global online video community in celebration of the people and platforms shaping the future of content, and we’re excited to join forces as we look to expand our slate of original digital programming and partnerships.”VidCon’s Louderback said: Viacom’s expansive reach across all of our key constituents will give us the opportunity to expand our global footprint more rapidly.“We’re also looking forward to their expertise in pioneering and executing live fan-first events – from the Video Music Awards and BET Experience to Comedy Central’s ClusterFest – as we continue to make VidCon a life-changing experience for those that create and love online video.”Last year, Viacom launched Comedy Central’s first comedy and pop culture event ClusterFest, while Paramount Network’s Bellator MMA (mixed martial arts event) visited New York’s Madison Square Garden for the first time.The first VidCon event took place in Los Angeles in 2010 and the online video conference now takes place three times a year in Anaheim California, Amsterdam and Melbourne.Louderback was appointed VidCon CEO last year. He was previously CEO of Revision3, a multichannel network that was acquired by Discovery in 2012.
ShareTweet “We are out of sync with health services in places such as Scotland with people locally having to go private if they need more than one cycle at a cost of thousands of pounds per cycle.“Sinn Féin support the case for equal access to 3 cycles in line with NICE guidelines and a review of emotional support as recently outlined in our policy document ‘A Vision for Women’s Healthcare’.“I want to commend the Fairness in Fertility campaign, for raising these very important issues and for facilitating the difficult conversations to highlight the plight of many people who are struggling to access fertility services,” she added.Mullan commends Fairness in Fertility campaign was last modified: October 31st, 2018 by John2John2 Tags: Fairness in FertilityFOYLE MLAKAREN MULLANMullan commends Fairness in Fertility campaignSinn Feinstormont SINN Féin MLA Karen Mullan has commended the Fairness in Fertility campaign who presented senior health officials with 10,000 petition signatures calling for equal access to 3 cycles. Speaking after hosting the group at Stormont, the Foyle MLA said: “Many people face a very difficult and often hidden journey to access fertility services. “Today is another step forward on that journey through the presenting of 10,000 petition signatures to the Permanent Secretary in the Department of Health.
Copyright 2018 NPR. To see more, visit http://www.npr.org/.
Chinese authorities say they are investigating a batch of medication that is suspected to be tainted with HIV. According to local media, the batch contains more than 12,000 doses of human immunoglobulin — intravenous treatments used to boost weakened immune systems. China’s National Health Commission said in a statement that on Tuesday it asked medical institutions to stop using the suspect medicine, seal it and monitor any patients who might be impacted. It launched a recall of the product, which it says was produced by Shanghai Xinxing Pharmaceutical Company.”A group of experts sent by the National Medical Products Administration has arrived in Shanghai for site inspection at the company,” the state-run Xinhua News Agency reported. “All the related production and inspection records have been sealed.”The South China Morning Post describes the company as a “biotech company specialising in the production and sale of blood-based medical products,” and says it is controlled by a state-owned company. It’s not yet clear whether any patients contracted HIV from the medication. The National Health Commission said “experts believe that the risk of HIV infection in patients using the drug is very low.”Tainted medical products aren’t a new issue in China. Historically, blood transfusions are a common way that HIV has spread in the country. And there has been a pattern of rural residents contracting HIV as they sold blood, as NPR’s Anthony Kuhn reported nearly a decade ago. Avert, an HIV and AIDS organization, said that in the 1990s “negligent blood donation activities” cause a “dramatic increase in the spread of HIV across China.” China has taken steps to tackle the issue, the organization added, and “in 2010 the government announced that all collected blood products were screened for HIV.”Last year, according to the BBC, Chinese authorities announced that the “number of people contracting HIV [through transfusions] has been reduced to almost zero.” Instead, most of the new cases were contracted sexually. Still, the number of people in China known to be living with HIV is rising. The Economist recently reported that Chinese authorities say about 850,000 people are HIV positive – “almost three times the number in 2010.” However, that’s likely due to better detection and more testing options, the publication says. Copyright 2019 NPR. To see more, visit https://www.npr.org.
May 4, 2016 Next Article This story originally appeared on Reuters Reuters 256shares Add to Queue Struggling teen apparel retailer Aeropostale Inc. filed for Chapter 11 bankruptcy protection on Wednesday, succumbing to years of losses as shoppers moved on to fast-fashion retailers and online competitors.Aeropostale said it plans to finance its operations during its bankruptcy through a $160 million loan from Crystal Financial LLC combined with operating cash flow, according to a court filing.The company said it expects to emerge out of bankruptcy within six months with a resolution of its disputes with former shareholder Sycamore Partners, which had thrown a lifeline of $150 million to the retailer in 2014.”Aeropostale will likely emerge from Chapter 11 as a leaner entity with a smaller, but largely profitable, store base…but it does not solve the issue of relevance to the market,” said Neil Saunders, chief executive of research firm Conlumino.The mall-based retailer said it would close 113 U.S. stores and all 41 stores in Canada.”Rethinking the brand proposition is key to improving prospects. Chapter 11 buys Aero time and space to undertake this rethink. In itself does not provide a long-term solution,” Saunders said.The difficult market for teen apparel has triggered bankruptcy filings by high-profile retailers such as American Apparel Inc., Quiksilver Inc. and Sports Authority Inc. in the past year.Online retailers and fast-fashion retailers such as H&M, Forever 21 and Inditex’s Zara have posed a threat to traditional apparel retailers, but American Eagle Outfitters Inc.and Abercrombie & Fitch Co. have managed to turn around their businesses by controlling inventories and responding faster to changing fashion trends.Aeropostale said in March it was exploring strategic alternatives, including a sale, citing a dispute with a vendor, MGF Sourcing US, an affiliate of Sycamore Partners.Established by R.H. Macy’s & Co in the early 1980s, Aeropostale made its stock market debut in 2002 but the New York Stock Exchange delisted the shares in April.The company operated 739 Aeropostale stores in 50 states and Puerto Rico and 25 P.S. from Aeropostale stores in 12 states, as of May 1.The company listed assets in the range of $100 million to $500 million, and liabilities of $100 million to $500 millionThe case is in U.S. Bankruptcy Court, District of New York, Case No: 16-11275.(Reporting By Aurindom Mukherjee and Subrat Patnaik in Bengaluru; Editing by Sunil Nair and Don Sebastian) Aeropostale Learn how to successfully navigate family business dynamics and build businesses that excel. Free Webinar | July 31: Secrets to Running a Successful Family Business Image credit: Roberto Machado Noa | Getty Images 2 min read Teen Apparel Chain Aeropostale Files for Bankruptcy Protection Register Now »
Source:https://www.leibniz-ipht.de/en/institute/presse/news/detail/den-neuronen-bei-der-arbeit-zusehen-forscher-des-leibniz-ipht-machen-bislang-verborgene-prozesse-im.html Reviewed by James Ives, M.Psych. (Editor)Nov 28 2018It is the first time, scientists are able to achieve high-resolution observations of neuronal structures inside deep brain areas of living mice – by the use of the most minimally invasive endoscopic probe reported thus far. Using a hair-thin optical fiber, the researchers can look into deep brain areas of a living mouse as if through a keyhole. Recently introduced methods for holographic control of light propagation in complex media enable the use of a multimode fiber as an imaging tool. Based on this new approach, the scientists designed a compact system for fluorescence imaging at the tip of a fiber, offering a much smaller footprint as well as enhanced resolution compared to conventional endoscopes based on fiber bundles or graded-index lenses.”We are very excited to see our technology making its first steps towards practical applications in neuroscience,” says Dr Sergey Turtaev from Leibniz-IPHT, lead author of the paper. “For the first time, we have shown that it is possible to examine deep brain regions of a living animal model in a minimally invasive way and to achieve high-resolution images at the same time,” adds IPHT scientist Dr Ivo T. Leite. Sergey and Ivo work in the research group for Holographic Endoscopy led by IPHT scientist Prof. Tomáš Čižmár, who developed the holographic method for imaging through a single fiber. Using this approach, the research team succeeded in obtaining images of brain cells and neuronal processes in the visual cortex and hippocampus of living mice with resolution approaching one micrometer (i.e. one thousand times smaller than a millimeter). Detailed observations within these areas are crucial for research into sensory perception, memory formation, and severe neuronal diseases such as Alzheimer’s. Current investigation methods are strongly invasive, such that it is not possible to observe neuronal networks in these inner regions at work without massive destruction of the surrounding tissue – usual endoscopes comprised of hundreds of optical fibers are too large to penetrate such sensitive brain regions, while the neuronal structures are too tiny to be visualized by non-invasive imaging methods such as magnetic resonance imaging (MRI).Related StoriesRepurposing a heart drug could increase survival rate of children with ependymomaNeural pathways explain the relationship between imagination and willingness to helpWearing a hearing aid may mitigate dementia risk“This minimally invasive approach will enable neuroscientists to investigate functions of neurons in deep structures of the brain of behaving animals: without perturbing the neuronal circuits in action, it will be possible to reveal the activity of these neuronal circuits while the animal is exploring an environment or learning a new task,” explains project partner Dr Nathalie Rochefort from the University of Edinburgh.Building up on this work, the research team now wants to address the current challenges of neuroscience, which will entail the delivery of advanced microscopy techniques through single fibre endoscopes. “Under the “Photonics for Life” flag of the Leibniz-IPHT and in the scope of the European Research Council funded project LIFEGATE, we will strive hard to prepare more significant advancements on this result, essentially funneling the most advanced methods of modern microscopy deep inside the tissues of living and functioning organisms,” concludes Prof. Tomáš Čižmár.
Source:https://www.isglobal.org/documents/10179/7035461/Obesidad+y+contaminacion+EnvInt_eng.pdf/d46e263c-40f2-4bc6-9de1-a62a3a90b548 Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 31 2019Exposure to air pollution, particularly at school, could be associated with a higher risk of overweight and obesity during childhood. This is the conclusion of a study by the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa”, performed with 2,660 children between 7 and 10 years of age from 39 schools in Barcelona.A few studies have associated exposure to air pollution with a higher risk of child obesity and overweight. However, these studies focused mainly on exposure at home, without considering the school environment.The study, published in Environment International and performed under the BREATHE project, assessed for the first time the relation between obesity and overweight risk and air pollution levels at school and home, the two microenvironments where schoolchildren spend most of their time.Related StoriesRepurposing a heart drug could increase survival rate of children with ependymomaWhy Mattresses Could be a Health Threat to Sleeping ChildrenResearchers identify gene mutations linked to leukemia in children with Down’s syndromeOn one hand, the research team collected data on the children’s weight and height and calculated their body mass index and obesity and overweight status. On the other hand, they used sensors in the schoolyard to measure the levels of outdoor pollution – nitrogen dioxide (NO2), elemental carbon (EC), particle matter (PM2.5) and ultrafine particles -during one week in summer and another week in winter. They also estimated exposure levels to NO2, NOx, PM2.5, PM10 and PMcoarse at the home address.”We observed that children exposed to medium or high levels of air pollution at school -ultrafine particles, NO2, PM2.5 and EC- had a higher risk of obesity and overweight as compared to those exposed to lower levels”, concludes first author Jeroen de Bont, researcher at ISGlobal and IDIAP Jordi Gol. Exposure to high levels of PM10 at home was also associated with higher risk of obesity or overweight during childhood, although in this case the analysis was done with estimates of exposure levels.”The study has however some limitations, which means that the results are to be cautiously interpreted”, says Martine Vrijheid, ISGlobal researcher and study coordinator. “Being a cross-sectional study, we only have data at one time-point, and we do not have enough data to establish the nature of the association. To draw more solid conclusions, we need new longitudinal studies that follow the study participants over time”, she adds.Regarding the mechanisms linking air pollution and overweight, some animal studies suggest that pollution can induce oxidative stress, insulin resistance and systemic inflammation, factors that are known to contribute to obesity”, explains de Bont.Most children were exposed to air pollution levels above those recommended by the World Health Organisation (WHO), both at school and home. Specifically, over 75% were exposed to PM2.5 levels above those recommended (10μg/m3) and more than 50% breathed NO2 levels above those considered as safe (40μg/m3).
Reviewed by Alina Shrourou, B.Sc. (Editor)May 7 2019A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system. They found a type of leukocyte called neutrophils aggregate inside the capillaries during sepsis-induced acute lung injury (ALI), leading to disturbances and dead space in blood microcirculation.According to the researchers, this phenomenon is responsible for tissue hypoxia causing lung damage in the sepsis model, and mitigating neutrophils improves microcirculation as well as hypoxia.The lungs are responsible for exchanging oxygen with carbon dioxide gases during the breathing process, providing an essential function for sustaining life. This gas exchange occurs in the alveoli, each surrounded by many capillaries containing the circulating red blood cells.Researchers have been making efforts to observe microcirculation in alveoli, but it has been technically challenging to capture high-resolution images of capillaries and red blood cells inside the lungs that are in constant breathing motion.Professor Pilhan Kim from the Graduate School of Medical Science and Engineering and his team developed an ultra-fast laser scanning confocal microscope and an imaging chamber that could minimize the movement of a lung while preserving its respiratory state. They used this technology to successfully capture red blood cell circulation inside the capillaries of animal models with sepsis.During the process, they found that hypoxia was induced by the increase of dead space inside the lungs of a sepsis model, a space where red blood cells do not circulate. This phenomenon is due to the neutrophils aggregating and trapping inside the capillaries and the arterioles. It was also shown that trapped neutrophils damage the lung tissue in the sepsis model by inhibiting microcirculation as well as releasing reactive oxygen species.Related StoriesAPPG report highlights need to improve identification and treatment of sepsisStudy explains why several clinical trials of treatments for sepsis have been failedScientists identify mechanism that makes babies more likely than adults to die from sepsisFurther studies showed that the aggregated neutrophils inside pulmonary vessels exhibit a higher expression of the Mac-1 receptor (CD11b/CD18), which is a receptor involved in intercellular adhesion, compared to the neutrophils that normally circulate. Additionally, they confirmed that Mac-1 inhibitors can improve inhibited microcirculation, ameliorate hypoxia, while reducing pulmonary edema in the sepsis model.Their high-resolution 3D intravital microscope technology allows the real-time imaging of living cells inside the lungs. This work is expected to be used in research on various lung diseases, including sepsis.The research team’s pulmonary circulation imaging and precise analytical techniques will be used as the base technology for developing new diagnostic technologies, evaluating new therapeutic agents for various diseases related to microcirculation.Professor Kim said, “In the ALI model, the inhibition of pulmonary microcirculation occurs due to neutrophils. By controlling this effect and improving microcirculation, it is possible to eliminate hypoxia and pulmonary edema – a new, effective strategy for treating patients with sepsis.”Their 3D intravital microscope technology was commercialized through IVIM Technology, Inc., which is a faculty startup at KAIST. They released an all-in-one intravital microscope model called ‘IVM-CM’ and ‘IVM-C’. This next-generation imaging equipment for basic biomedical research on the complex pathophysiology of various human diseases will play a crucial role in the future global bio-health market. Source:https://www.kaist.ac.kr/_prog/_board/?code=ed_news&mode=V&no=95804&upr_ntt_no=95804&site_dvs_cd=en&menu_dvs_cd=060101